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Pion helps you make more informed decisions about candidate selection & formulation earlier in development

Accelerate your pharmaceutical formulation development with next-generation technology. As a leading drug formulation company, Pion supports your research with in vitro scientific instruments, analytical services and equipment to deliver the accuracy of results required for more predictive decision-making in the drug development process. 

Looking for a specific dissolution apparatus, analytical instrument or in-vivo predictive tool? Here’s where you’ll find it.

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Rainbow R6 

In-situ fiber optic UV-Vis spectrometer for dissolution, absorption, flux and solubility studies

The Rainbow R6 concentration monitor is an in-situ fiber optic UV-Vis spectrometer with a Deuterium lamp light source and photodiode array detection. It is a powerful analytical instrument that correctly and accurately measures dissolution in real-time.

Common Applications

  • Dissolution testing
  • Drug solubility
  • Dissolution monitoring
  • Absorption and Flux assays

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Sirius T3

Automated platform for the determination of Physicochemical Properties

The SiriusT3 is an essential tool for solubility testing by analyzing pure single-component organic chemicals and their salts. It measures pKa, logP, logD and solubility of ionizable drugs and small molecules, needing only very small amounts of sample. It is widely used in industrial and university labs, CROs and Pharma to support drug discovery research.  It generates detailed information about the extent and duration of supersaturation and a pH-solubility profile from a single, highly automated assay that takes less than 2 hours.

Common Applications

  • Determining intrinsic solubility
  • Measuring pKa in synthetic chemistry to help select the best structures for development
  • Understanding the ionization state of a drug, how it varies with pH and its effect on absorption
  • Physicochemical Characterization

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SCISSOR N3

In vitro subcutaneous injection site simulator

Scissor N3 is an in vitro model simulating subcutaneous injection of biopharmaceuticals for rank ordering formulations and excipient screening during formulation development. The first instrument designed to specifically assess the risk and performance of subcutaneously administered drugs, including biologics, peptides, and small molecules. 

Common Applications

  • Excipient screening during formulation development
  • Formulation comparison 
  • Rank ordering formulations for candidate selection
  • Investigation of drug stability upon and after injection

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Why Choose Pion?

Pion’s quick response time to our service needs keeps downtime to a minimum in our lab.

QC Director
Tennessee

They truly care about the customer experience and the financial impacts on our company.

Company President
Florida

Pion’s service is the gold standard for our industry. They are in a league by themselves!

QC Supervisor
North Carolina

Advance your program with next-generation pharmaceutical development and technology from Pion.